The actor and musician played guitar with his longtime friend Jeff Beck at a concert at Sheffield City Hall in in Sheffield, England.
Depp is no stranger to music. He, along with musicians Alice Cooper and Joe Perry, formed the super group Hollywood Vampires in 2012.
The jury in his defamation trial with his ex-wife Amber Heard began deliberations on Friday.
Depp sued Heard over a 2018 op-ed for the Washington Post in which she described herself as a “public figure representing domestic abuse.” Though Depp was not named in the article, he claims it affected his reputation and lost him work.
Heard has filed a counterclaim for $100 million.